Abstract While macrophage phagocytosis is an immune defense mechanism against invading cellular organisms, cancer cells expressing the Connection Tube CD47 ligand send forward signals to repel this engulfment.Here we report that the reverse signaling using CD47 as a receptor additionally enhances a pro-survival function of prostate cancer cells und
Deubiquitination of CDC6 by OTUD6A promotes tumour progression and chemoresistance
Abstract Background CDC6 is an oncogenic protein whose expression level fluctuates during the cell cycle.Although several E3 ubiquitin ligases responsible for the ubiquitin-mediated proteolysis of CDC6 have been identified, the deubiquitination pathway for CDC6 has not been investigated.Methods The proteome-wide deubiquitinase (DUB) screening Colle
Criopreservação de ovócitos de bovinos imaturos desnudados ou não, utilizando o etilenoglicol pelo método da vitrificação Cryopreservation of bovines immature oocytes desnudes or not, by the ethylene glycol vitrification method
Objetivou-se avaliar os efeitos da vitrificação em ovócitos de bovinos após o cultivo in vitro, utilizando o etilenoglicol como crioprotetor.Ovócitos obtidos de ovários de vacas abatidas em matadouro foram distribuídos aleatoriamente em três tratamentos.Tratamento 0 (testemunha): ovócitos não-desnudados e não-congelados.Tratamento 1: vit
Thermal Comfort Analysis in Rooms Using Low Temperature Convective and Radiant Heating Terminals
The concept of energy is closely related to the building sector and the systems used for heating, implicitly energy saving which is a current problem of both old and new buildings.In this paper a series of numerical simulations were made in Hand and feet set Autodesk CFD Simulation in order to study the influence of terminal heating systems over th
Genome-wide identification and evolution-profiling analysis of tps gene family in Camphora longepaniculata and screening of key TPS genes
Camphora longepaniculata is an important economic crop renowned for its rich volatile terpene compounds.Terpene synthases (TPS) are key enzymes in the biosynthesis of these compounds, playing significant Garters roles in plant growth, development, and secondary metabolism.In this study, a total of 86 TPS genes were identified in Camphora longepanic